产品货号：
Z38289
中文名称：
HDAC3抗体
英文名称：
Anti-HDAC3 Antibody (Clone#OTI4E10)
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-HDAC3 Antibody (Clone#OTI4E10) |
| 指标别名 | HD3;HDAC3;histone deacetylase 3;RPD3;RPD3 2;SMAP45 |
| 克隆性 | Monoclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB |
| 基因名称 | HDAC3 |
| 克隆号 | OTI4E10 |
| 抗体来源 | Mouse |
| 抗体类型 | IgG2a |
| 免疫原 | Human recombinant protein fragment corresponding to amino acids 1-235 of human HDAC3(NP_003874) produced in E.coli. |
| 实际分子量 | 48.7KD |
| 成分 | PBS (PH 7.3) containing 1% BSA,50% glycerol and 0.02% sodium azide. |
| 纯化方式 | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | Stable for 12 months from date of receipt.Store at -20℃ as received. |
| 背景资料 | HDAC3(HISTONE DEACETYLASE 3) is a member of the histone deacetylase/acuc/apha family of proteins that is an enzyme that in humans is encoded by the HDAC3 gene.The HDAC3 gene is mapped to 5q31.3.HDAC3 has histone deacetylase activity and represses transcription when tethered to a promoter.It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1.The protein can also down-regulate p53 function and thus modulate cell growth and apoptosis.And this gene is regarded as a potential tumor suppressor gene.HDAC3 has an open reading frame of 428 amino acids and shares 53% amino acid identity with HDAC1 and 52% with HDAC2.The catalytic domain of HDAC4 interacts with HDAC3 via the transcriptional corepressor NCOR2.All experimental conditions leading to the suppression of HDAC4 binding to NCOR2 and to HDAC3 resulted in loss of enzymatic activity associated with HDAC4.HDAC3 recruitment to the genome displays a circadian rhythm in mouse liver. |
| Uniprot ID | O15379 |
| 基因名全称 | histone deacetylase 3 |
| 蛋白名全称 | Histone deacetylase 3(HD3) |
| 推荐稀释比 | Western blot (WB) 1:2000 |
相关搜索：HDAC3抗体，HDAC3单抗，Anti-HDAC3 Antibody (Clone#OTI4E10)